abstract：PURPOSE:To report the incidence and outcomes of intraoperative Descemet membrane (DM) perforations during deep anterior lamellar keratoplasty (DALK). DESIGN:Retrospective, consecutive, interventional case series. METHODS:A retrospective audit of all DALK cases performed from 2004 to 2015 in a tertiary center, with an...

journal_title：American journal of ophthalmology

authors： Huang OS,Htoon HM,Chan AM,Tan D,Mehta JS

更新日期：2019-03-01 00:00:00

abstract：PURPOSE:To determine whether a machine learning technique called Kalman filtering (KF) can accurately forecast future values of mean deviation (MD), pattern standard deviation, and intraocular pressure for patients with normal tension glaucoma (NTG). DESIGN:Development and testing of a forecasting model for glaucoma p...

journal_title：American journal of ophthalmology

authors： Garcia GP,Nitta K,Lavieri MS,Andrews C,Liu X,Lobaza E,Van Oyen MP,Sugiyama K,Stein JD

更新日期：2019-03-01 00:00:00

abstract：PURPOSE:To evaluate the relationships among age-related macular degeneration (AMD), mortality, and biomarkers of systemic inflammation in patients with acquired immunodeficiency syndrome (AIDS). DESIGN:Case-control study. METHODS:In participants with intermediate-stage AMD at enrollment in the Longitudinal Study of t...

journal_title：American journal of ophthalmology

authors： Jabs DA,Van Natta ML,Trang G,Jones NG,Milush JM,Cheu R,Klatt NR,Danis RP,Hunt PW

更新日期：2019-03-01 00:00:00

abstract：PURPOSE:We sought to analyze the incidence and risk of noninfectious uveitis (NIU) among postdelivery women with a history of pre-eclampsia/eclampsia (PEE). DESIGN:Population-based retrospective matched cohort study. METHODS:All participant data were retrieved from the Longitudinal Health Insurance Database 2005. Two...

journal_title：American journal of ophthalmology

authors： Chen WD,Yang YH,Lee CY,Lai CH,Liu CY,Lai LJ

更新日期：2019-02-01 00:00:00

abstract：OBJECTIVE:To document the clinical presentation, treatment, and visual outcome of sarcoid uveitis and to determine the timing and potential risk factors of sarcoidosis progression to symptomatic systemic disease from the time of sarcoid uveitis diagnosis. DESIGN:Retrospective, interventional case series. METHODS:Subj...

journal_title：American journal of ophthalmology

authors： Ma SP,Rogers SL,Hall AJ,Hodgson L,Brennan J,Stawell RJ,Lim LL

更新日期：2019-02-01 00:00:00

abstract：PURPOSE:To determine if the use of oral contraceptive pills (OCP) and other hormonal contraceptives are associated with a higher incidence of idiopathic intracranial hypertension (IIH). DESIGN:Retrospective, population-based, case-control study. METHODS:Setting: Female IIH patients evaluated between January 1, 1990, ...

journal_title：American journal of ophthalmology

authors： Kilgore KP,Lee MS,Leavitt JA,Frank RD,McClelland CM,Chen JJ

更新日期：2019-01-01 00:00:00

abstract：PURPOSE:To identify associations between severity of sickle cell retinopathy (SCR) and other clinical, laboratory, or treatment factors relevant to sickle cell disease (SCD). DESIGN:Retrospective cohort study. METHODS:We investigated clinical, laboratory, and demographic associations with the severity of SCR in 296 p...

journal_title：American journal of ophthalmology

authors： Duan XJ,Lanzkron S,Linz MO,Ewing C,Wang J,Scott AW

更新日期：2019-01-01 00:00:00

abstract：PURPOSE:To analyze the risk factors, clinical characteristics, management, and treatment outcomes of culture-proven cases of Moraxella keratitis at our center. DESIGN:Retrospective observational case series. METHODS:Thirty-nine culture-proven cases of Moraxella keratitis (39 eyes) diagnosed and treated between Januar...

journal_title：American journal of ophthalmology

authors： Durrani AF,Faith SC,Kowalski RP,Yu M,Romanowski E,Shanks R,Dhaliwal D,Jhanji V

更新日期：2019-01-01 00:00:00

abstract：PURPOSE:To investigate visual outcome and prognostic factors following cataract surgery in patients with Vogt-Koyanagi-Harada (VKH) disease. DESIGN:Retrospective, interventional case series. METHODS:The history, clinical characteristics, best-corrected visual acuity (BCVA), full-field electroretinogram (ERG), intraoc...

journal_title：American journal of ophthalmology

authors： Ji Y,Hu K,Li C,Li P,Kijlstra A,Eghrari AO,Lei B,Du L,Wan W,Yang P

更新日期：2018-12-01 00:00:00

abstract：PURPOSE:To compare race-related differences in estimated rate of change of Bruch's membrane opening-minimum rim width (BMO-MRW) and circumpapillary retinal nerve fiber layer thickness (RNFLT) in healthy, glaucoma suspect, and glaucoma eyes of individuals of European (ED) and African descent (AD). DESIGN:Prospective co...

journal_title：American journal of ophthalmology

authors： Bowd C,Zangwill LM,Weinreb RN,Girkin CA,Fazio MA,Liebmann JM,Belghith A

更新日期：2018-12-01 00:00:00

abstract：PURPOSE:To identify factors related to graft rejection following Descemet stripping automated endothelial keratoplasty (DSAEK) in the Cornea Preservation Time Study (CPTS). DESIGN:Cohort study within a multicenter randomized clinical trial. METHODS:A total of 1330 eyes of 1090 subjects undergoing DSAEK were randomize...

journal_title：American journal of ophthalmology

authors： Stulting RD,Lass JH,Terry MA,Benetz BA,Cohen NJ,Ayala AR,Maguire MG,Croasdale C,Daoud YJ,Dunn SP,Goins KM,Gupta PC,Macsai MS,Mian SI,Pramanik S,Rose-Nussbaumer J,Song JC,Stark WJ,Sugar A,Verdier DD,Szczotka-Flynn

更新日期：2018-12-01 00:00:00

abstract：PURPOSE:To study the glistening formation in various hydrophobic-acrylic intraocular lens (IOL) models, and to evaluate the effect of glistenings on light scattering in these IOLs. DESIGN:Laboratory investigation. METHODS:The susceptibility of the hydrophobic-acrylic material to develop glistenings was evaluated in 6...

journal_title：American journal of ophthalmology

authors： Łabuz G,Knebel D,Auffarth GU,Fang H,van den Berg TJ,Yildirim TM,Son HS,Khoramnia R

更新日期：2018-12-01 00:00:00

abstract：PURPOSE:Central retinal artery occlusion (CRAO) is mechanistically similar to a stroke. Current guidelines recommend a standardized and systematic evaluation of risk factors for patients who have had a stroke. This study evaluates the yield of this evaluation in patients with CRAO and frequency of stroke in this popula...

journal_title：American journal of ophthalmology

authors： Lavin P,Patrylo M,Hollar M,Espaillat KB,Kirshner H,Schrag M

更新日期：2018-12-01 00:00:00

abstract：PURPOSE:To report the long-term outcomes of intravitreal anti-vascular endothelial growth factor (VEGF) treatment for diabetic macular edema (DME) in a real-world clinical setting and to assess the efficacy of subsequent alternative treatments in eyes with suboptimal response to anti-VEGF. DESIGN:Retrospective interve...

journal_title：American journal of ophthalmology

authors： Maggio E,Sartore M,Attanasio M,Maraone G,Guerriero M,Polito A,Pertile G

更新日期：2018-11-01 00:00:00

abstract：PURPOSE:To evaluate the diagnostic performance characteristics of the Van Herick assessment (VHA) for identifying angle closure compared to gold-standard gonioscopy, as conducted by trained observers of varying expertise. DESIGN:Reliability analysis. METHODS:Patients (n = 131) from a glaucoma referral clinic aged ≥50...

journal_title：American journal of ophthalmology

authors： Johnson TV,Ramulu PY,Quigley HA,Singman EL

更新日期：2018-11-01 00:00:00

abstract：PURPOSE:Noninfectious uveitis has been treated historically with corticosteroid therapy in varying doses and routes. Triesence, a preservative-free sterile formulation of triamcinolone acetonide, has been used in a wide spectrum of ocular pathologies, but there have been few large studies validating its dosing or detai...

journal_title：American journal of ophthalmology

authors： Ganapathy PS,Lowder CY,Arepalli S,Baynes K,Li M,Bena J,Srivastava SK

更新日期：2018-10-01 00:00:00

abstract：PURPOSE:To correlate in vivo imaging to histology in an eye with macular atrophy owing to age-related macular degeneration (AMD; complete retinal pigment epithelium [RPE] and outer retinal atrophy [cRORA]) to evaluate the utility of new optical coherence tomography (OCT) suggested by previous histology. DESIGN:Case st...

journal_title：American journal of ophthalmology

authors： Dolz-Marco R,Balaratnasingam C,Messinger JD,Li M,Ferrara D,Freund KB,Curcio CA

更新日期：2018-09-01 00:00:00

abstract：PURPOSE:Diseases that involve retinal or choroidal vascular endothelial cells are leading causes of vision loss: age-related macular degeneration, retinal ischemic vasculopathies, and noninfectious posterior uveitis. Proteins differentially expressed by these endothelial cell populations are potential drug targets. We ...

journal_title：American journal of ophthalmology

authors： Smith JR,David LL,Appukuttan B,Wilmarth PA

更新日期：2018-09-01 00:00:00

abstract：PURPOSE:To investigate the natural history of Stargardt disease (STGD1) using fixation location and fixation stability. DESIGN:Multicenter, international, prospective cohort study. METHODS:Fixation testing was performed using the Nidek MP-1 microperimeter as part of the prospective, multicenter, natural history study...

journal_title：American journal of ophthalmology

authors： Schönbach EM,Strauss RW,Kong X,Muñoz B,Ibrahim MA,Sunness JS,Birch DG,Hahn GA,Nasser F,Zrenner E,Sadda SR,West SK,Scholl HPN,ProgStar Study Group.

更新日期：2018-09-01 00:00:00

abstract：PURPOSE:Comparative evaluation of complications and visual outcomes following bilateral congenital cataract surgery in children up to 2 years of age with and without primary intraocular lens (IOL) implantation at 5 years follow-up. DESIGN:Randomized controlled clinical trial. METHODS:Sixty children (120 eyes) up to 2...

journal_title：American journal of ophthalmology

authors： Vasavada AR,Vasavada V,Shah SK,Praveen MR,Vasavada VA,Trivedi RH,Rawat F,Koul A

更新日期：2018-09-01 00:00:00

abstract：PURPOSE:To characterize the locations, circumstances, and outcomes of falls in patients with varying degrees of glaucoma. DESIGN:Prospective cohort study. METHODS:Patients with suspected or diagnosed glaucoma completed monthly calendars reporting falls. After each fall, a 30-item questionnaire was administered to det...

journal_title：American journal of ophthalmology

authors： Sotimehin AE,Yonge AV,Mihailovic A,West SK,Friedman DS,Gitlin LN,Ramulu PY

更新日期：2018-08-01 00:00:00

abstract：PURPOSE:To evaluate microbiota colonizing soft contact lenses (CL) in eyes with Boston type I keratoprosthesis (BKPro), and determine the prevalence of resistance to fourth-generation fluoroquinolone (FQ). DESIGN:Prospective, observational study. SUBJECTS:Patients with BKPro using CL as routine who were in postoperat...

journal_title：American journal of ophthalmology

authors： Torres-Netto EA,Silva LD,Bordon Riveros MA,Santos A,Sousa LB,Oliveira LA

更新日期：2018-08-01 00:00:00

abstract：PURPOSE:To determine whether ocular phenotypic features of keratoconjunctivitis sicca (KCS) and/or participant-reported symptoms of dry eye disease are associated with depression in women participants enrolled in the Sjögren's International Collaborative Clinical Alliance (SICCA). DESIGN:Cross-sectional study. METHOD...

journal_title：American journal of ophthalmology

authors： Gonzales JA,Chou A,Rose-Nussbaumer JR,Bunya VY,Criswell LA,Shiboski CH,Lietman TM

更新日期：2018-07-01 00:00:00

abstract：PURPOSE:To describe a novel imaging technique, which we call "dense B-scan optical coherence tomography angiography" (DB OCTA), in which thin dense raster scans are used to produce highly resolved structural B-scans with superimposed flow signal that provide precise correlation between retinal microstructure and blood ...

journal_title：American journal of ophthalmology

authors： Freund KB,Gattoussi S,Leong BCS

更新日期：2018-06-01 00:00:00

abstract：PURPOSE:To review the contributions to ophthalmic genetics through the American Journal of Ophthalmology (AJO). DESIGN:Perspective. METHODS:A literature search to retrieve original articles, letters, editorials, and published lectures from 1966 to 2017, providing a 50-year review. Titles were excluded that gave no re...

journal_title：American journal of ophthalmology

authors： MacDonald IM,Sieving PC

更新日期：2018-06-01 00:00:00

abstract：PURPOSE:To study the association between peripheral changes in age-related macular degeneration (AMD) and dark adaptation (DA). DESIGN:Prospective, cross-sectional study. METHODS:We recruited patients with AMD and a control group (>50 years) without any vitreoretinal disease. Ultra-widefield (UWF) pseudocolor and fun...

journal_title：American journal of ophthalmology

authors： Laíns I,Park DH,Mukai R,Silverman R,Oellers P,Mach S,Kim IK,Vavvas DG,Miller JW,Miller JB,Husain D

更新日期：2018-06-01 00:00:00

abstract：PURPOSE:To establish the medium-term repeatability of the iPad perimetry app Melbourne Rapid Fields (MRF) compared to Humphrey Field Analyzer (HFA) 24-2 SITA-standard and SITA-fast programs. DESIGN:Multicenter longitudinal observational clinical study. METHODS:Sixty patients (stable glaucoma/ocular hypertension/glauc...

journal_title：American journal of ophthalmology

authors： Prea SM,Kong YXG,Mehta A,He M,Crowston JG,Gupta V,Martin KR,Vingrys AJ

更新日期：2018-06-01 00:00:00

abstract：PURPOSE:To assess the long-term stability of sutured scleral-fixated posterior chamber intraocular lenses (PCIOLs) performed in combination with pars plana vitrectomy. DESIGN:Retrospective, consecutive, interventional case series. METHODS:Retrospective single-surgeon study of 118 eyes of 111 patients seen at Retina C...

journal_title：American journal of ophthalmology

authors： Kokame GT,Yanagihara RT,Shantha JG,Kaneko KN

更新日期：2018-05-01 00:00:00

abstract：PURPOSE:To use the capillary-free zone along retinal arteries, a physiologic area of superficial avascularization, as an anatomic paradigm to investigate the reliability of optical coherence tomography angiography (OCTA) for visualizing the deep retinal circulation. DESIGN:Validity analysis and laboratory investigatio...

journal_title：American journal of ophthalmology

authors： Balaratnasingam C,An D,Sakurada Y,Lee CS,Lee AY,McAllister IL,Freund KB,Sarunic M,Yu DY

更新日期：2018-05-01 00:00:00

abstract：PURPOSE:To describe the relationship between the incidence of age-related macular degeneration (AMD) and nonsteroidal anti-inflammatory drug (NSAIDs) use. DESIGN:Prospective cohort study. METHODS:This study consisted of participants in the California Men's Health Study. Those who completed surveys in 2002-2003 and 20...

journal_title：American journal of ophthalmology

authors： Modjtahedi BS,Fong DS,Jorgenson E,Van Den Eeden SK,Quinn V,Slezak JM

更新日期：2018-04-01 00:00:00

abstract：PURPOSE:To investigate the prevalence of peripheral pigmented retinal lesions and associated clinical findings in patients with Stargardt disease. DESIGN:Retrospective case series. METHODS:Records at a single academic institution were reviewed for patients with genetically confirmed Stargardt disease with peripheral ...

journal_title：American journal of ophthalmology

authors： Zhao PY,Abalem MF,Nadelman D,Qian CX,Branham K,Schlegel D,Khan N,Heckenlively JR,Jayasundera T

更新日期：2018-04-01 00:00:00

abstract：PURPOSE:To analyze the long-term growth patterns of type 1 neovascularization (NV) in eyes with age-related macular degeneration (AMD) receiving anti-vascular endothelial growth factor (VEGF) therapy. DESIGN:Retrospective cohort study. METHODS:Patients were enrolled from 2 eye centers and underwent optical coherence ...

journal_title：American journal of ophthalmology

authors： Xu D,Dávila JP,Rahimi M,Rebhun CB,Alibhai AY,Waheed NK,Sarraf D

更新日期：2018-03-01 00:00:00

abstract：PURPOSE:To investigate the role of corneal hysteresis (CH) as a risk factor for development of glaucoma. DESIGN:Prospective observational cohort study. METHODS:Two hundred and eighty-seven eyes of 199 patients suspected of having glaucoma were followed for an average of 3.9 ± 1.8 years. All eyes had normal visual fie...

journal_title：American journal of ophthalmology

authors： Susanna CN,Diniz-Filho A,Daga FB,Susanna BN,Zhu F,Ogata NG,Medeiros FA

更新日期：2018-03-01 00:00:00

abstract：PURPOSE:To evaluate the rate of peripapillary choroidal thinning in glaucoma patients and healthy controls using spectral domain optical coherence tomography. DESIGN:Cohort study. METHODS:Participants from the multicenter African Descent and Glaucoma Evaluation Study and Diagnostic Innovations in Glaucoma Study were ...

journal_title：American journal of ophthalmology

authors： Mundae RS,Zangwill LM,Kabbara SW,Hammel N,Bowd C,Medeiros FA,Girkin CA,Liebmann JM,Weinreb RN,Belghith A

更新日期：2018-02-01 00:00:00

abstract：PURPOSE:To measure the area of the optic nerve subarachnoid space (ONSASA) in patients with normal tension glaucoma (NTG), primary open-angle glaucoma (POAG), and controls and examine its association with relevant ocular and systemic parameters. DESIGN:Cross-sectional study. METHODS:The study included 40 patients wit...

journal_title：American journal of ophthalmology

authors： Liu H,Yang D,Ma T,Shi W,Zhu Q,Kang J,Wang N

更新日期：2018-02-01 00:00:00

abstract：PURPOSE:To evaluate low- vs high-dose plaque brachytherapy for juxtapapillary choroidal melanoma. DESIGN:Retrospective interventional case series. METHODS:Setting: Single institution. STUDY POPULATION:Forty-seven patients with juxtapapillary choroidal melanoma. INTERVENTION:Iodine-125 plaque brachytherapy. Eyes wer...

journal_title：American journal of ophthalmology

authors： Oellers P,Mowery YM,Perez BA,Stinnett S,Mettu P,Vajzovic L,Light K,Steffey BA,Cai J,Dutton JJ,Buckley EG,Halperin EC,Marks LB,Kirsch DG,Mruthyunjaya P

更新日期：2018-02-01 00:00:00

abstract：PURPOSE:To expand our understanding of the uncommon entity, referred to as perifoveal exudative vascular anomalous complex (PEVAC) by describing multimodal imaging findings, including optical coherence tomography angiography (OCT-A). DESIGN:Retrospective cohort study. METHODS:Patients diagnosed with PEVAC were identi...

journal_title：American journal of ophthalmology

authors： Sacconi R,Freund KB,Yannuzzi LA,Dolz-Marco R,Souied E,Capuano V,Semoun O,Phasukkijwatana N,Sarraf D,Carnevali A,Querques L,Bandello F,Querques G

更新日期：2017-12-01 00:00:00

abstract：PURPOSE:To investigate whether use of donors predisposed by corneal collagen cross-linking (CXL) reduced myopic refractive errors for keratoconic eyes after penetrating keratoplasty (PK). DESIGN:Randomized controlled trial. METHODS:One hundred sixteen eyes of 116 patients with keratoconus from Zhongshan Ophthalmic Ce...

journal_title：American journal of ophthalmology

authors： Huang T,Ye R,Ouyang C,Hou C,Hu Y,Wu Q

更新日期：2017-12-01 00:00:00

abstract：PURPOSE:To evaluate the disease extent on ultra-widefield fundus autofluorescence (UWF-FAF) in patients with ABCA4 Stargardt disease (STGD) and correlate these data with functional outcome measures. DESIGN:Retrospective cross-sectional study. METHODS:Setting: Kellogg Eye Center, University of Michigan. STUDY POPULAT...

journal_title：American journal of ophthalmology

authors： Abalem MF,Otte B,Andrews C,Joltikov KA,Branham K,Fahim AT,Schlegel D,Qian CX,Heckenlively JR,Jayasundera T

更新日期：2017-12-01 00:00:00

abstract：PURPOSE:To determine characteristics of peri-dome choroidal deepening (PDCD) surrounding dome-shaped maculas (DSMs) in highly myopic eyes. DESIGN:Observational case series. METHODS:Applying swept-source optical coherence tomography, we examined the posterior pole of highly myopic eyes with DSMs. RESULTS:The study in...

journal_title：American journal of ophthalmology

authors： Ohno-Matsui K,Fang Y,Uramoto K,Shinohara K,Yokoi T,Ishida T,Jonas JB

更新日期：2017-11-01 00:00:00